иммунотактоидная гломерулопатия

Новые аспекты патофизиологии и патоморфологии поражений почек при злокачественных опухолях

КЛИНИКА, ДИАГНОСТИКА И ЛЕЧЕНИЕ ЛИМФОИДНЫХ ОПУХОЛЕЙ , , , , , ,

Б.Т. Джумабаева, Л.С. Бирюкова

ФГБУ «Гематологический научный центр» Минздрава России, Новый Зыковский пр-д, д. 4а, Москва, Российская Федерация, 125167

Для переписки: Болдукыз Толгонбаевна Джумабаева, д-р мед. наук, Новый Зыковский пр-д., д. 4а, Москва, Российская Федерация, 125167; тел.: +7(495)613-24-68; e-mail: bola.blood@yandex.ru

Для цитирования: ДДжумабаева Б.Т., Бирюкова Л.С. Новые аспекты патофизиологии и патоморфологии поражений почек при злокачественных опухолях. Клиническая онкогематология. 2015;8(4):390–396.

DOI: 10.21320/2500-2139-2015-8-4-379-389

РЕФЕРАТ

Поражение клубочков почек при злокачественных опухолях встречается редко и носит морфологически гетерогенный характер. Несмотря на то что патоморфологическая взаимосвязь между опухолью и гломерулопатией не достаточно ясна, за последние десятилетия стали известны некоторые молекулярные механизмы паранеопластических гломерулопатий и патоморфологические особенности поражения почек при солидных опухолях, злокачественных лимфо- и миелопролиферативных заболеваниях.

Ключевые слова: мембранозная нефропатия, иммунотактоидная гломерулопатия, гломерулопатия с минимальными изменениями, фибриллярный гломерулонефрит, почечная недостаточность, анти-PLA2R1-антитело, белок c-mip.

Получено: 19 марта 2015 г.

Принято в печать: 23 октября 2015 г.

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