Клиническая онкогематология. Фундаментальные исследования и клиническая практика
Clinical Oncohematology. Basic Research and Clinical Practice
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ISSN 2500-2139 (online)
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Clinical Oncohematology
Basic Research and Clinical Practice

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  • Effect of Bruton Tyrosine Kinase Inhibitors on T-Lymphocytes and Tumor Microenvironment Cells in B-Cell Lymphoproliferative Diseases

    Yuliya Sergeevna Efremova, T.V. Glazanova, N.A. Romanenko
    320-326
    01.07.2026
  • Blastoid Variant of Cyclin D1-Negative Mantle Cell Lymphoma in a Female Patient with 46,XY Disorder of Sex Development: A Rare Case Report

    Natalia Vyacheslavovna Oparina, T.V. Davidian, E.A. Mamaeva, N.G. Chernova, L.A. Tsapkova, N.A. Bodunova
    353-362
    01.07.2026
  • High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation in the Third- and Subsequent-Line Therapy for Relapsed/Refractory Classical Hodgkin Lymphoma

    Vladislav Olegovich Sarzhevskiy, Yu.V. Protopopova, N.E. Mochkin, E.A. Demina, A.A. Mamedova, A.A. Samoylova, V.S. Bogatyrev, A.A. Rukavisyn, E.G. Smirnova, N.S. Shorokhov, A.E. Bannikova, V.Ya. Melnichenko
    310-319
    01.07.2026
  • Level and Serum Metabolism of Homocysteine in Chronic Myeloid Leukemia Patients: A Literature Review

    K.S. Samarina, Yuliana Yurevna Assesorova, I.V. Berger
    162-171
    01.04.2026
  • NK-Cell Receptor Repertoire in Chronic Myeloid Leukemia

    Tamara Vangelevna Chitanava, R.A. Vlasik, L.O. Khordzhasov, A. Ataman, N.S. Luchkina, A.Yu. Aronov, I.D. Matvienko, N.T. Siordiya, O.V. Kulemina, N.S. Lazorko, E.I. Sbityakova, N.A. Shnalieva, E.N. Tochenaya, J.A. Alekseeva, P.A. Butylin, S.V. Smirnov, Yu. A. Zaritskii, Yu.P. Martinova, E.G. Lomaia
    152-161
    01.04.2026
  • Results of a Double-Blind Prospective Comparative Randomized Phase 3 Clinical Trial of the Efficacy and Safety of BCD-264 and Darzalex as Monotherapy for Relapsed/Refractory Multiple Myeloma (BCD-264-2/DARVIVA)

    T.V. Shelekhova, J. Kumar, S.J. Apte, Iu.S. Osipov, E.N. Misyurina, V.A. Doronin, T.S. Konstantinova, B.A. Bakirov, A.V. Proidakov, A.L. Uss, M. Kumar, E.V. Martynova, N.G. Chernova, M.A. Khokhar, A.D. Garifullin, C.R. Ross, S.L. Cyriac, S.V. Voloshin, M.A. Ulyanova, N.A. Falaleeva, N.A. Katin, D.V. Kirtbaya, M.O. Kiseleva, E.Yu. Komarceva, A.A. Myasnikov, D.K. Novik, M. Shabbir-Moosajee, S.V. Samarina, V.V. Denisova, G.N. Khusainova, T.K. Dolai, B. Bagchi, I.S. Zyuzgin, I.S. Moiseev, T.I. Pospelova, A.A. Semenova, M.A. Novikova, I.L. Davydkin, M.V. Kosinova, A.M. Pavlova, N. Sidharthan, H. Mukhopadhyay, A. Wahid, Q.M. Buttar, Yu.N. Linkova, A.V. Zinkina-Orikhan, Svyatoslav Vladimirovich Nechaev, A.S. Shadrina, A.A. Lutckii, D.O. Liaptseva
    119-130
    01.04.2026
  • Bruton Tyrosine Kinase Inhibitors for the Treatment of Mantle Cell Lymphoma: A Literature Review and Our Own Experience

    Ulyana Gordeevna Koshkina, A.A. Semenova, M.Yu. Kichigina, D.N. Tupitsyna, V.O. Shpirko, A.I. Cherencova, S.F. Ramazanova, N.O. Zemlyakov, I.Z. Zavodnova, A.V. Arakelyan, G.D. Petrova, O.Yu. Baranova, G.S. Tumyan
    59-69
    01.01.2026
  • Bruton Tyrosine Kinase Inhibitors for the Treatment of Relapsed Mantle Cell Lymphoma Involving CNS: Two Case Reports and Literature Review

    Evgenii Olegovich Kunevich, N.N. Nemstsveridze, M.A. Mikhaleva, A.Yu. Kuvshinov, T.V. Ovchinnikova, E.V. Koryakina, S.V. Samarina, K.Yu. Krutikova, S.V. Sidorkevich, S.V. Voloshin
    184-196
    01.04.2025
  • Functional Cure as a New Concept of Therapy for Multiple Myeloma

    Sergei Vyacheslavovich Semochkin
    105-120
    01.04.2025
  • Options for Program Chemotherapy and Their Outcomes in Patients with Newly Diagnosed Mantle Cell Lymphoma Based on the Data from a Single Center

    Ulyana Gordeevna Koshkina, G.S. Tumyan, A.A. Semenova, M.Yu. Kichigina, I.Z. Zavodnova, D.N. Tupitsyna, E.V. Paramonova, A.S. Antipova, V.O. Shpirko, Yu.I. Klyuchagina, S.F. Ramazanova, A.V. Arakelyan, G.D. Petrova, O.Yu. Baranova, N.A. Kupryshina, E.A. Osmanov
    121-133
    01.04.2025
  • Current Strategy and Principles of Multiple Myeloma Treatment: A Literature Review

    Aleksander Sergeevich Luchinin, A.A. Semenova, S.V. Semochkin
    153-162
    01.04.2025
  • Personalized Approach to Treatment of Newly Diagnosed Diffuse Large B-Cell Lymphoma Patients with Respect to Molecular Landscape: A Case Report and Literature Review

    Marat Albertovich Mingalimov, E.A. Baryakh, T.N. Tolstykh, A.V. Misyurin, L.A. Kesaeva, A.S. Mkrtchyan, A.M. Kovrigina, E.N. Misyurina, M.S. Orlova, T.S. Chudnova, D.D. Ivanova, O.L. Kochneva, S.S. Andreev, K.V. Yatskov, I.V. Samsonova, M.A. Lysenko
    177-183
    01.04.2025
  • Iron Metabolism in Patients with Paroxysmal Nocturnal Hemoglobinuria: Results of a Single-Center Ambispective Clinical Trial

    Vitalii Dmitrievich Latyshev, K.A. Jennewein, A.A. Soloveva, A.E. Kitsenko, N.V. Tsvetaeva, E.A. Lukina
    1-9
    01.01.2025
  • The Role of Somatic Mutations in Various Genes and the Issue of Resistance to Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients: A Literature Review

    Elena Andreevna Kuzmina, E.Yu. Chelysheva, B.V. Biderman, A.G. Turkina
    10-20
    01.01.2025
  • Interim Results of the Russian Prospective Multi-Center Clinical Trial READIT-2020 (Reduction of Tyrosine Kinase Inhibitor Doses in CML Patients, Plasma Imatinib/Nilotinib Concentrations, Sustaining Molecular Response, and Drug Toxicity)

    Margarita Anatolevna Gurianova, V.I. Kazey, O.A. Shukhov, E.Yu. Chelysheva, A.G. Nikiforova, P.D. Sobolev, M.S. Dolov, D.Yu. Grebenkin, A.N. Petrova, A.V. Bykova, I.S. Nemchenko, E.A. Kuzmina, L.V. Gavrilova, A.V. Kokhno, A.G. Turkina
    347-359
    01.10.2024
  • Sarcoid-like Pulmonary Lesion in a Female Patient with Multiple Myeloma and Systemic AL Amyloidosis Treated with Daratumumab: A Case of Spontaneous Regression of Lung Tissue Changes upon Drug Withdrawal

    Irina Germanovna Rekhtina, V.A. Khyshova, A.M. Kovrigina, M.A. Silaev, L.P. Mendeleeva
    370-375
    01.10.2024
  • Response-Adapted Strategy in the Treatment of Primary Mediastinal Large B-Cell Lymphoma: Results of a Prospective Single-Center Clinical Trial

    Yana Konstantinovna Mangasarova, R.R. Abdurashidova, A.U. Magomedova, O.V. Margolin, E.S. Nesterova, L.G. Gorenkova, M.O. Bagova, E.A. Fastova, D.S. Belkina, A.M. Kovrigina, N.G. Gabeeva, D.A. Koroleva, S.K. Kravchenko, Yu.A. Chabaeva, E.E. Zvonkov
    335-346
    01.10.2024
  • Treatment Outcomes in Primary Mediastinal Large B-Cell Lymphoma. Experience of the AF Tsyb Medical Radiological Research Center (Obninsk)

    Alena Yurevna Terekhova, N.A. Falaleeva, A.B. Galitsyna, A.M. Chelmakov, A.A. Vovchenko, N.A. Riabikina, A.A. Danilenko, T. I. Bogatyreva
    225-236
    01.07.2024
  • Nivo-DHAP Combined with Subsequent High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation in Patients with Relapsed/Refractory Classical Hodgkin Lymphoma: Results of a Multi-Center Prospective Clinical Trial (ClinicalTrials.gov, NCT04091490)

    V.O. Sarzhevskii, Aisel Akifovna Mamedova, N.E. Mochkin, E.A. Demina, A.A. Spornik, A.A. Samoilova, V.S. Bogatyrev, A.A. Rukavitsyn, E.G. Smirnova, N.S. Shorokhov, A.E. Bannikova, V.Ya. Melnichenko, N.B. Mikhailova, E.S. Borzenkova, L.V. Stelmakh, Yu.R. Zalyalov, A.A. Semenova, G.S. Tumyan, M.A. Danilova, O.A. Konova, N.A. Falaleeva, AYu Terekhova, M.A. Vernyuk, A.M. Chervontseva, L.S. Khairullina, A.A. Maslov, I.B. Lysenko, Yu.A. Alekseeva, E.S. Pavlyuchenko, A.A. Mirsaitov, A.A. Zverkova, I.V. Ishmatova, S.A. Volchenkov, M.S. Motalkina, I.S. Zyuzgin
    1-10
    17.05.2024
  • Cardiovascular Complications of the Immunotherapy of Hematological Malignancies: A Literature Review

    Geliya Rifkatovna Gimatdinova, O.E. Danilova, V.P. Kuzmin, G.I. Davydkin, Yu.V. Kostalanova, D.A. Kudlai, I.L. Davydkin
    407-412
    28.09.2023
  • Treatment Outcomes with Asciminib, the First Allosteric BCR::ABL1 Tyrosine Kinase Inhibitor, in Chronic Myeloid Leukemia Patients with Multiple Resistance to Prior Therapy

    A.G. Turkina, Elena Andreevna Kuzmina
    311-320
    09.06.2023
  • Multiple Myeloma Complicated by Bone Plasmacytomas: Pathogenesis, Clinical Features, Treatment Approaches (A Literature Review)

    Elizaveta Andreevna Mamaeva, M.V. Solov’eva, L.P. Mendeleeva
    303-310
    09.06.2023
  • Nivo-BeGEV as Preparation for Autologous Hematopoietic Stem Cell Transplantation in Relapsed/Refractory Classical Hodgkin Lymphoma: Results of a Multi-Center Prospective Clinical Study

    Yana Konstantinovna Mangasarova, T.N. Moiseeva, O.V. Margolin, L.G. Gorenkova, E.S. Nesterova, F.E. Babaeva, M.O. Bagova, E.A. Fastova, R.R. Abdurashidova, L.S. Al-Radi, E.I. Dorokhina, E.M. Volodicheva, V.A. Lapin, O.S. Samoilova, S.K. Kravchenko, A.U. Magomedova, E.E. Zvonkov
    280-286
    09.06.2023
  • Classical Hodgkin Lymphoma: Tumor Structure and Prognostic Value of the Immune Microenvironment

    Artem Aleksandrovich Gusak, K.V. Lepik, L.V. Fedorova, V.V. Markelov, V.V. Baykov
    242-262
    09.06.2023
  • Perspectives for the Use of Immunomodulatory Drugs and Cereblon E3 Ligase Modulators in the Treatment of Multiple Myeloma

    Sergei Vyacheslavovich Semochkin
    229-241
    09.06.2023
  • KIR-Genetic Factors and Response to Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia

    Elena Vital’evna Kuzmich, I.E. Pavlova, L.N. Bubnova, S.S. Bessmeltsev
    119-127
    03.03.2023
  • Efficacy and Toxicity of Induction Therapy in Patients with Newly Diagnosed Systemic AL Amyloidosis: Results of a Prospective Single-Center Clinical Study

    I.G. Rekhtina, Viktoriya Aleksandrovna Khyshova, M.V. Solov’ev, L.P. Mendeleeva
    166-173
    03.03.2023
  • Ibrutinib Efficacy in First-Line Therapy of High-Risk Patients Vs. Second- and Third-Line Therapies of Resistant Chronic Lymphocytic Leukemia

    Nadezhda Viktorovna Kurkina, E.A. Repina, P.V. Volkova, A.A. Repin
    209-212
    03.03.2023
  • Combination of Ibrutinib and Venetoclax in the Therapy of Chronic Lymphocytic Leukemia: A Review of the Latest Data from Clinical Studies

    A.A. Petrenko, Mariya Igorevna Kislova, E.A. Dmitrieva, E.A. Nikitin, V.V. Ptushkin
    37-45
    01.01.2023
  • Gilteritinib as a New Option for the Treatment of Relapsed/Refractory Acute Myeloid Leukemias with FLT3 Gene Mutation: A Literature Review and Three Case Reports

    D.V. Motorin, L.L. Girshova, E.G. Lomaia, Yu.A. Alekseeva, A.V. Petukhov, V.V. Ivanov, E.K. Antonov, S.V. Efremova, A.I. Reshetova, E.N. Tochenaya, Aleksina Alekseevna Shatilova, E.N. Tochenaya, A.V. Petrov, T.S. Nikulina, K.V. Bogdanov, D.V. Ryzhkova, Yu.V. Mirolyubova, I.E. Prokop’ev, I.G. Budaeva
    69-79
    01.01.2023
  • Efficacy of Combined Drug Pre-transplant Conditioning Regimens in Multiple Myeloma Patients with Single Autologous Hematopoietic Stem Cell Transplantation

    Ivan Ivanovich Kostroma, A.S. Zhuk, Zh.Yu. Sidorova, R.R. Sabitova, A.Yu. Aksenova, O.B. Belopolskaya, S.S. Bessmeltsev, S.V. Sidorkevich, S.V. Gritsaev
    88-95
    01.01.2023
  • CAR-T Therapy of Multiple Myeloma, Based on the Congresses ASH-2021 and ASCO-2022

    Sergei Vyacheslavovich Semochkin
    1-13
    01.01.2023
  • Asciminib in Chronic Myeloid Leukemia Patients Without Therapeutic Alternatives: Results of the MAP (Managed Access Program, NCT04360005) Trial in Russia

    A.G. Turkina, Elena Andreevna Kuzmina, E.G. Lomaia, E.V. Morozova, E.Yu. Chelysheva, O.A. Shukhov, A.N. Petrova, T.V. Chitanava, Yu.Yu. Vlasova, I.S. Nemchenko, A.V. Bykova, E.I. Sbityakova, M.A. Gurianova, N.N. Tsyba, A.V. Kokhno, E.N. Parovichnikova
    54-68
    01.01.2023
  • Efficacy Predictors of the Third-Line Tyrosine Kinase Inhibitor Therapy in Patients with Chronic Phase of Chronic Myeloid Leukemia: Results of a Multi-Center Study

    E.G. Lomaia, V.A. Shuvaev, Tamara Vangelevna Chitanava, Yu.D. Matvienko, I.S. Martynkevich, S.V. Voloshin, E.V. Efremova, E.S. Mileeva, M.S. Fominykh, A.E. Kersilova, E.V. Karyagina, N.V. Il’ina, N.V. Dorofeeva, N.V. Medvedeva, A.V. Klimovich, T.V. Shneider, S.A. Stepanova, N.F. Polezhaikovskaya, N.T. Siordiya, E.I. Sbityakova, N.S. Lazorko, E.N. Tochenaya, D.V. Motorin, N.A. Shnalieva, Yu.A. Alekseeva, D.B. Zammoeva, A.Yu. Zaritskey
    271-281
    01.07.2022
  • Russian Prospective Non-Randomized Clinical Study on Dose Reduction of Tyrosine Kinase Inhibitors with Subsequent Complete Therapy Discontinuation in Chronic Myeloid Leukemia Patients with Stable Deep Molecular Response (READIT-2020): Background, Aim, Mai

    A.G. Turkina, Margarita Anatolevna Gurianova, E.Yu. Chelysheva, O.A. Shukhov
    54-61
    01.01.2022
  • Biological Mechanisms of Sustaining Deep Molecular Response in Chronic Myeloid Leukemia Upon Withdrawal of Tyrosine Kinase Inhibitors

    Ekaterina Yurevna Chelysheva, M.A. Guryanova, A.G. Turkina
    427-435
    01.10.2021
  • Langerhans Cell Histiocytosis in Adults: Treatment Opportunities of Today

    Vitalii Dmitrievich Latyshev, E.A. Lukina
    444-454
    01.10.2021
  • Prediction of Treatment Efficacy in Relapsed Chronic Lymphocytic Leukemia

    Olga Borisovna Kalashnikova, I.S. Moiseev, T.L. Gindina, E.A. Izmailova, M.O. Ivanova, E.V. Kondakova, N.B. Mikhailova, A.D. Kulagin
    466-476
    01.10.2021
  • Treatment of Mastocytosis: A Literature Review

    Karina Maksimovna Chernavina, A.S. Orlova, E.A. Nikitin
    361-369
    01.07.2021
  • Opportunities of Chronic Myeloid Leukemia Treatment with Reduced Doses of Tyrosine Kinase Inhibitors

    Margarita Anatolevna Guryanova, E.Yu. Chelysheva, A.G. Turkina
    118-128
    01.01.2021
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