Quality of Life of Patients with Lymphomas at Different Time-Points after High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation

N.E. Mochkin, D.A. Fedorenko, V.Ya. Mel’nichenko, T.I. Ionova, T.P. Nikitina, K.A. Kurbatova, A.A. Novik,

DOI:

https://doi.org/10.21320/2500-2139-2014-7-4-577-582

The article presents results of monitoring of quality of life of 103 patients with lymphomas (non-Hodgkin’s lymphomas, n = 36; Hodgkin’s lymphomas, n = 67) at different stages after high-dose chemotherapy with autologic hematopoietic stem cell transplantation (HDC + HSCT). The majority of patients experienced improvement or stabilization of their quality of life 1 year after the HDC + aHSCT. At that, the response associated with the quality of life and clinical response to the treatment did not coincide in all cases. Obtained results confirm the importance of a comprehensive approach to assessment of the efficacy of the treatment and may be use as a principle marker of patient’s recovery at different time points after the transplantation.

  • N.E. Mochkin N.I. Pirogov National Medical and Surgical Center under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203 ; ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» МЗ РФ, ул. Нижняя Первомайская, д. 70, Москва, Российская Федерация, 105203
  • D.A. Fedorenko N.I. Pirogov National Medical and Surgical Center under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203 ; ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» МЗ РФ, ул. Нижняя Первомайская, д. 70, Москва, Российская Федерация, 105203
  • V.Ya. Mel’nichenko N.I. Pirogov National Medical and Surgical Center under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203 ; ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» МЗ РФ, ул. Нижняя Первомайская, д. 70, Москва, Российская Федерация, 105203
  • T.I. Ionova International Quality of Life Research Center, 1 office 152, Artilleriiskaya str., Saint Petersburg, Russian Federation, 191014 ; Межнациональный центр исследования качества жизни, ул. Артиллерийская, д. 1, офис 152, Санкт-Петербург, Российская Федерация, 191014
  • T.P. Nikitina N.I. Pirogov National Medical and Surgical Center under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203; International Quality of Life Research Center, 1 office 152, Artilleriiskaya str., Saint Petersburg, Russian Federation, 191014 ; ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» МЗ РФ, ул. Нижняя Первомайская, д. 70, Москва, Российская Федерация, 105203; Межнациональный центр исследования качества жизни, ул. Артиллерийская, д. 1, офис 152, Санкт-Петербург, Российская Федерация, 191014
  • K.A. Kurbatova International Quality of Life Research Center, 1 office 152, Artilleriiskaya str., Saint Petersburg, Russian Federation, 191014 ; Межнациональный центр исследования качества жизни, ул. Артиллерийская, д. 1, офис 152, Санкт-Петербург, Российская Федерация, 191014
  • A.A. Novik N.I. Pirogov National Medical and Surgical Center under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203 ; ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» МЗ РФ, ул. Нижняя Первомайская, д. 70, Москва, Российская Федерация, 105203
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  • N.E. Mochkin, PhD, assistant, N.I. Pirogov National Medical and Surgical Center under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203, ФГБУ «Национальный медико-хирургический центр им. Н.И. Пирогова» МЗ РФ, ул. Нижняя Первомайская, д. 70, Москва, Российская Федерация, 105203, e-mail: nickmed@yandex.ru

Published

01.10.2014

Issue

QUALITY OF LIFE

How to Cite

Mochkin N.E., Fedorenko D.A., Mel’nichenko V.Y., et al. Quality of Life of Patients with Lymphomas at Different Time-Points after High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation. Clinical Oncohematology. Basic Research and Clinical Practice. 2014;7(4):577–582. doi:10.21320/2500-2139-2014-7-4-577-582.

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