Primary Breast Lymphoma in a 30-Year-Old Female Patient: A MALT Lymphoma or Pediatric Nodal Marginal Zone Lymphoma? A Case Report and Literature Review

Primary lymphoma accounts for less than 0.5 % of all breast malignancies. One of the most ubiquitous diseases in this group is extranodal lymphoma of mucosa-associated marginal zone lymphoid tissue (MALT lymphoma). Pediatric nodal marginal zone lymphoma is a rare indolent B-cell malignancy similar to the pediatric follicular lymphoma in its clinical and molecular genetic features. These variants of pediatric indolent B-cell lymphomas are known to have favorable prognosis. The present paper reports a case of pediatric nodal marginal zone lymphoma in an intramammary lymph node of a 30-year-old female patient with previously core-biopsy proven breast MALT lymphoma. A reliable diagnosis is of clinical significance and requires a detailed examination along with the analysis of all clinical/anamnestic, physical examination and laboratory data as well as extended biopsy sampling to assure sufficient amount of diagnostically relevant information.

• Mariya Vladimirovna Melnikova National Research Center for Hematology, 4 Novyi Zykovskii pr-d, Moscow, Russian Federation, 125167 https://orcid.org/0009-0003-1694-6861 (unauthenticated)
• A.M. Kovrigina National Research Center for Hematology, 4 Novyi Zykovskii pr-d, Moscow, Russian Federation, 125167 ; IM Sechenov First Moscow State Medical University, 2 korp. 4 Bolshaya Pirogovskaya ul., Moscow, Russian Federation, 119435 https://orcid.org/0000-0002-1082-8659 (unauthenticated)

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