Infectious Complications in Multiple Myeloma under Current Epidemiological Conditions: A Literature Review

The review outlines current views on immune system in multiple myeloma (MM) and the basic pathogens inducing infectious complications in such patients. Although in recent years there has been considerable progress in studying molecular mechanisms of the MM development (pathogenesis), methods of its diagnosis, treatment, and prediction of outcomes, one of the main causes of death within this group of patients is infectious complications. In this context, it would be relevant to further study immune disorders and the spectrum of infectious pathogens common in the MM patient cohort. The study and correction of immunological status can contribute to improving the MM outcomes, which in turn will lead to increased life expectancy.

• I.L. Davydkin Samara State Medical University, 89 Chapaevskaya str., Samara, Russian Federation, 443099 ; ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России, ул. Чапаевская, д. 89, Самара, Российская Федерация, 443099
• Elizaveta Vladimirovna Mordvinova Samara State Medical University, 89 Chapaevskaya str., Samara, Russian Federation, 443099 ; ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России, ул. Чапаевская, д. 89, Самара, Российская Федерация, 443099
• T.P. Kuzmina Samara State Medical University, 89 Chapaevskaya str., Samara, Russian Federation, 443099 ; ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России, ул. Чапаевская, д. 89, Самара, Российская Федерация, 443099

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