Use of Blinatumomab in Acute Lymphoblastic Leukemia in Municipal Healthcare: A Case Report

Acute lymphoblastic leukemia is one of the groups of most challenging malignant neoplasms of hematopoietic tissue. Despite the success in achieving remission induction in primary patients, later, most of them develop disease relapses. Overall and disease-free survivals have to be improved, which cannot be achieved solely with chemotherapy intensification. The new target drugs and cell technologies improve the treatment options for the resistant forms and relapses of acute lymphoblastic leukemia. The effective use of new drugs presupposes their timely assignment which can be ensured by their availability in routine clinical practice. The provided case report describes the successful use of bispecific antibody blinatumomab for treating an early relapse of acute lymphoblastic leukemia in the clinical practice within the municipal healthcare system.

• Vasilii Anatolevich Shuvaev VV Veresaev Municipal Clinical Hospital, 10 Lobnenskaya str., Moscow, Russian Federation, 127644; Russian Research Institute of Hematology and Transfusiology, 16 2-ya Sovetskaya str., Saint Petersburg, Russian Federation, 191024 ; ГБУЗ «Городская клиническая больница им. В.В. Вересаева» ДЗМ, Москва, Российская Федерация, ул. Лобненская, д. 10, Москва, Российская Федерация, 127644; ФГБУ «Российский НИИ гематологии и трансфузиологии ФМБА России», ул. 2-я Советская, д. 16, Санкт-Петербург, Российская Федерация, 191024
• O.V. Ushakova VV Veresaev Municipal Clinical Hospital, 10 Lobnenskaya str., Moscow, Russian Federation, 127644 ; ГБУЗ «Городская клиническая больница им. В.В. Вересаева» ДЗМ, Москва, Российская Федерация, ул. Лобненская, д. 10, Москва, Российская Федерация, 127644
• E.I. Mullo VV Veresaev Municipal Clinical Hospital, 10 Lobnenskaya str., Moscow, Russian Federation, 127644 ; ГБУЗ «Городская клиническая больница им. В.В. Вересаева» ДЗМ, Москва, Российская Федерация, ул. Лобненская, д. 10, Москва, Российская Федерация, 127644
• T.V. Tolstykh VV Veresaev Municipal Clinical Hospital, 10 Lobnenskaya str., Moscow, Russian Federation, 127644 ; ГБУЗ «Городская клиническая больница им. В.В. Вересаева» ДЗМ, Москва, Российская Федерация, ул. Лобненская, д. 10, Москва, Российская Федерация, 127644
• N.Z. Triputen VV Veresaev Municipal Clinical Hospital, 10 Lobnenskaya str., Moscow, Russian Federation, 127644 ; ГБУЗ «Городская клиническая больница им. В.В. Вересаева» ДЗМ, Москва, Российская Федерация, ул. Лобненская, д. 10, Москва, Российская Федерация, 127644

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