Value of Patient-Reported Outcomes in Oncohematology

QUALITY OF LIFE , , ,

T.I. Ionova1, S. Salek2, Е. Оliva3

1 International Quality of Life Research Center, 1 office 152, Artilleriiskaya str., Saint Petersburg, Russian Federation, 191014

2 Cardiff University, Pharmacoeconomics Department, Redwood Building King Edward VII Avenue Cardiff, CF10 3NB, UK

3 Hematology Division, Azienda Ospedaliera B-M-M, Via Melacrino, 89100 Regio Calabria, Italy

For correspondence: T.I. Ionova, DSci, Professor, 1 office 152, Artilleriiskaya str., Saint Petersburg, Russian Federation, 191014; Tel: +7(812)579-61-38; e-mail: tation16@gmail.com

For citation: Ionova T.I., Salek S., Oliva E. Value of Patient-Reported Outcomes in Oncohematology. Klin. Onkogematol. 2014; 7(4): 573–576 (In Russ.).

ABSTRACT

One of priorities of modern medical science is the patient-oriented care. This approach presupposes that patient management should be based not only on analysis of clinical and lab test findings but also on reports made by the patient himself. These reports permit to perform a thorough analysis of patient’s problems and to obtain more data on the treatment effectiveness. Quality of life (QoL) and symptoms are key factors in patient-reported outcomes (PRO). The past decade has been characterized by increased attention paid by the medical community to patient’s own sensations throughout the treatment. The importance of this principle is confirmed by the fact that “Quality of Life in Hematology” was declared as the 2012–2013 theme of the year by the European Hematology Association. Partient-reported outcomes permit to obtain information that cannot be obtained from other sources. It is especially important when new treatment methods are selected and when new approaches to palliative care are developed.

Keywords: patient-reported outcomes, quality of life, symptoms, clinical practice.

Accepted: September 15, 2014

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REFERENCES

  1. Doward L.C., McKenna S.P. Defining patient-reported outcomes. Value Health. 2004; 7(Suppl. 1): S4–S8.
  2. Efficace F., Novik A., Vignetti M. et al. Health-related quality of life and symptom assessment in clinical research of patients with hematologic malignancies: where are we now and where do we go from here? Haematologica 2007; 92(12): 1596–8.
  3. Gorodokin G.I., Novik A.A. Quality of cancer care. Ann. Oncol. 2005; 16: 991. 4. Guidelines. Patient-reported outcomes in hematology. The EHA SWG «Quality of life and Symptoms». Forum Service Editore. Genoa, 2012.
  4. Osoba D. Translating the science of patient-reported outcomes assessment into clinical practice. J. N. C. I. Monogr. 2007; 37: 5–11.
  5. US Food and Drug Administration: Guidance for Industry. Patient-reported outcome measures: use in medical product development to support labeling claims. Available from website U.S. FDA, Clinical/Medical, 2009. http:/www.fda. gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ UCM193282.pdf.
  6. Руководство по исследованию качества жизни в медицине, 3-е изд., перераб. и доп. Под ред. Ю.Л. Шевченко. М.: Изд-во РАЕН, 2012. [Shevchenko Yu.L., ed. Rukovodstvo po issledovaniyu kachestva zhizni v meditsine (Guidelines for evaluation of the quality of life in medicine). 3rd revised edition. Moscow: RAEN Publ.; 2012.]
  7. World Health Organization: Constitution of the World Health Organization, in Handbook of Basic Documents. Geneva, 1948.
  8. Salek S., Ionova T., Oliva E., EHA SWG «Quality of Life and Symptoms». Patients’ needs in hematology: whose perspectives? Haematologica. 2013; 98(6): 828–30.
  9. Новик А.А., Ионова Т.И. Руководство по исследованию качества жизни в медицине. СПб.: Нева, ОЛМА-ПРЕСС Звездный мир. 2002. [Novik A.A., Ionova T.I. Rukovodstvo po issledovaniyu kachestva zhizni v meditsine. (Guidelines for evaluation of the quality of life in medicine.) Saint Petersburg: Neva, OLMA-PRESS Zvezdnyi mir Publ.; 2002.]
  10. Fayers P., Machin D. Quality of life: The assessment, analysis and interpretation of patient-reported outcomes. Weinheim: John Wiley & Sons, 2007.
  11. Fitzpatrick R., Davey C., Buxton M.J., Jones D.R. Evaluating patient-based outcome measures for use in clinical trials. Hlth. Technol. Ass. 1998; 2(14): 1–74.
  12. Strasser-Weippl K., Ludwig H. Psychosocial QOL is an independent predictor of overall survival in newly diagnosed patients with multiple myeloma. Eur. J. Haematol. 2008; 81(5): 374–9.
  13. Oliva E., Nobile F., Alimena F. et al. Quality of life in elderly patients with acute myeloid leukemia: patients may be more accurate than physicians. Haematologica. 2011; 96(5): 696–702.
  14. WHO Definition of Palliative Care. World Health Organization. Retrieved May, 2014