Pulmonary complications of high-dose chemotherapy and autologous hematopoietic stem cell transplantation in patients with hematological malignancies

V.O. Sarzhevskiy, V.Ya. Melnichenko, V.P. Tyurin

N.I. Pirogov National Medico-surgical Center, RF MH, Moscow, Russian Federation


ABSTRACT

This review presents the recent data on the pulmonary complications after high-dose chemotherapy and autologous hematopoietic stem cell transplantation in patients with hematological malignancies. The detailed information on the diagnostic approaches, pathogenetic and clinical features, prevention and treatment of the early and late pulmonary toxicity is provided.


Keywords: high-dose chemotherapy, autologous hematopoietic stem cell transplantation, pulmonary complications.

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