Anorexia-Cachexia Syndrome in Cancer Patients

MAINTENANCE THERAPY , ,

AV Snegovoi, IB Kononenko, VB Larionova, AI Saltanov, VYu Sel’chuk

N.N. Blokhin Russian Cancer Research Center, 24 Kashirskoye sh., Moscow, Russian Federation, 115478

For correspondence: Anton Vladimirovich Snegovoi, PhD, 24 Kashirskoye sh., Moscow, Russian Federation, 115478; Tel.: +7(499)324-41-09; e-mail: anvs2012@gmail.com

For citation: Snegovoi AV, Kononenko IB, Larionova VB, et al. Anorexia-Cachexia Syndrome in Cancer Patients. Clinical oncohematology. 2015;8(2):185–90 (In Russ).

ABSTRACT

For a long time, cachexia has been considered one of symptoms of cancer progression. The word cachexia is of Greek origin (kakos — bad and hexis — condition). This disorder is associated with a decrease in physical activity, reduced effectiveness of anticancer therapy, and decreased survival rates. The study of dissemination of malignancies demonstrated that cachexia is caused not only by the malignancy itself, but also by development of anorexia (loss of appetite) due to changes in humoral regulation of metabolic processes. Therefore, such condition of cancer patients should be called an anorexia-cachexia syndrome.

Keywords: anorexia-cachexia syndrome, cachexia, anorexia.

Received: February 3, 2015

Accepted: February 10, 2015

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