Unknown bacteria in oral flora of children with hematological malignancies

INFECTIONS IN ONCOHEMATOLOGY , , ,

M.F. Vecherkovskaya, G.V. Tetz, and V.V. Tetz

I.P. Pavlov Saint Petersburg State Medical University, Saint Petersburg, Russian Federation

ABSTRACT

The objective of this study was to investigate the oral flora of children with hematological malignancies. The variance in the oral microflora of healthy children and children with hematological malignancies are shown. An unknown bacterium was isolated from the mixed biofilms obtained from the saliva of children with hematological malignancies that was absent in the saliva of healthy children of the same age. The microbiological data combined with the proteome assessment and genome sequence analysis indicate that the isolated microorganism belongs to the previously undescribed Streptococcus species.

Keywords: uncultured bacteria, biofilms, microbiota, children

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