New Aspects of Pathophysiology and Pathomorphology of Renal Lesions in Malignant Tumors

LYMPHOID TUMORS , , , , , ,

B.T. Dzhumabaeva, L.S. Biryukova

Hematology Research Center under the Ministry of Health of the Russian Federation, 4а Novyi Zykovskii pr-d, Moscow, Russian Federation, 125167

For correspondence: Boldukyz Tolgonbaevna Dzhumabaeva, DSci, 4а Novyi Zykovskii pr-d, Moscow, Russian Federation, 125167; Tel.: +7(495)613-24-68; e-mail: bola.blood@yandex.ru

For citation: Dzhumabaeva BT, Biryukova LS. New Aspects of Pathophysiology and Pathomorphology of Renal Lesions in Malignant Tumors. Clinical oncohematology. 2015;8(4):390–396 (In Russ).

DOI: 10.21320/2500-2139-2015-8-4-390-396

ABSTRACT

Glomerular injuries associated with malignancy are rare and they are morphologically heterogeneous. Although the pathophysiologic interrelations between a tumor and glomerulopathy are not clear, molecular mechanisms of paraneoplastic glomerulopathies and pathologic features of renal lesions in solid tumors, lymphoproliferative and myeloproliferative disorders have been discovered over recent decades.

Keywords: membranous nephropathy, immunotactoid glomerulopathy, minimal-change glomerulopathy, fibrillary glomerulonephritis, renal failure, anti-PLA2R1 antibody, c-mip protein.

Received: March 19, 2015

Accepted: October 23, 2015

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